The Center for Innovation in E-Learning aims to support the university's vision of leading the employment of technology in education to contribute to national development. This is achieved through conducting quality research and initiatives in the field of e-learning, its methodologies, and technologies. The center will work on enhancing the research ecosystem within the university and establishes partnerships with distinguished researchers and research organizations locally and internationally.

The Scientific Colleges Research Center is at the forefront of scientific research and innovation, focusing on the leading scientific fields of our time, including computing, fintech, artificial intelligence, robotics, e-commerce, and administrative and financial sciences. The center is committed to providing a collaborative research environment that fosters advanced research and development in these specialized areas.

The Health Sciences Research Center was established in 2024 with the aim of connecting researchers from the college at the Saudi Electronic University with the community through investment, empowerment, and the activation of local and global partnerships. The College of health sciences affiliated with the university, spread across various regions of the Kingdom, and are home to a distinguished group of faculty members from diverse health and medical backgrounds, who represent an important contribution to national development in pursuit of and contribution to achieving the Saudi Vision 2030.